45+Research opportunities
50+Commercial whitespaces
35+Ecosystem support needs

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Key: Cultivated icon Cultivated Fermentation icon Fermentation Plant-based icon Plant-Based
Opportunity Production platform Value chain segment Technology sector End product focus Relevant actor Maturity level Solution category Topic
Optimizing fat profiles for nutritional and sensory properties

Because alternative meat’s fat content and fatty acid profile can be more easily controlled than conventional meat’s, there is an opportunity to alter fat content for nutritional benefits. Additional research…

Cultivated icon Cultivated Fermentation icon Fermentation Plant-based icon Plant-Based End Products Production R&D Cell culture media End product formulation & manufacturing Target molecule selection Seafood-relevant Academics Industry Startups Commercial Research Science
Mapping animal cell metabolism to optimize media formulation

The cost and environmental impact of cultivated meat are driven by the cell culture media formulation and its conversion efficiency into meat. Metabolic modeling and engineering techniques can aid media…

Cultivated icon Cultivated Production R&D Raw Materials, Ingredients, & Inputs Cell culture media Cell line development Species-agnostic Academics Industry Startups Commercial Research
Consumer education on the food safety of cultivated meat

Consumer education on the food safety of cultivated meat can positively impact consumer acceptance when sufficient information is provided. Additional research and efforts to increase transparent science communication on the…

Cultivated icon Cultivated Fermentation icon Fermentation Demand Generation End Products Species-agnostic Academics GFI Industry NGO’s Startups Ecosystem Science
Ensuring appropriate food safety controls for cultivated meat

Sterilization guidelines from well-established biomedical and food industries can act as helpful templates for safe cultivated meat production. However, more research is needed to identify potentially novel production hazards for…

Cultivated icon Cultivated Compliance Species-agnostic Ecosystem Policy Research Policy
Incorporating growth factors into scaffolds to reduce costs and introduce spatial heterogeneity

Growth factors (GFs) can be incorporated into scaffolds as a strategy for both reducing costs and improving product quality of cultivated meat. Open-access research is needed to test the feasibility…

Cultivated icon Cultivated End Products Production R&D Scaffolding Seafood-relevant Academics Industry Startups Commercial Research
Scaffolds and structural approaches to optimize fat distribution and content in cultivated meat

The inclusion of fat and marbling in cultivated meat is likely to increase its flavor, texture, and consumer appeal. Structural approaches using edible microcarriers, hydrogels, and 3D bioprinting present promising…

Cultivated icon Cultivated End Products Production R&D Raw Materials, Ingredients, & Inputs Bioprocess design End product formulation & manufacturing Scaffolding Species-agnostic Academics Industry Startups Commercial Research Industry Science
Promoting stemness and proliferation in fish cell cultures

Efficient and cost-effective cultivated fish production will require precise optimization to encourage fast proliferation and highly efficient use of inputs while preventing premature differentiation. A variety of strategies can be…

Cultivated icon Cultivated Production R&D Cell culture media Cell line development Seafood Academics Industry Startups Research Science
Hybrid products to optimize nutrition, taste, cost, and sustainability

Hybrid products are a promising means to improve the cost and sustainability of animal-derived meat while improving the taste of plant proteins. Promoting the health benefits of hybrids may facilitate…

Cultivated icon Cultivated Fermentation icon Fermentation Plant-based icon Plant-Based Demand Generation End Products Production R&D Raw Materials, Ingredients, & Inputs End product formulation & manufacturing Ingredient optimization Species-agnostic Academics Industry Investors Startups Commercial Industry Science
Cost-effective sterility controls for cultivated meat

Meticulous attention to sterility controls throughout cultivated meat production is essential to optimize food safety, but the cost of biopharmaceutical-based sterility—the current standard for cell-based processes—is incongruent with large-scale food…

Cultivated icon Cultivated Production Bioprocess design Cell culture media End product formulation & manufacturing Species-agnostic Industry Policymakers Startups Ecosystem Research Industry Policy Science
Scientist / engineer outreach and education

To expand the technical talent pipeline, various players in the alternative protein field should reach out to scientists and engineers in relevant disciplines (e.g., biotech, biopharma, and food science) to…

Cultivated icon Cultivated Fermentation icon Fermentation Plant-based icon Plant-Based Workforce Species-agnostic Academics Donors GFI Industry NGO’s Policymakers Startups Ecosystem

Get involved

If you’d like to fund a research project, work on any of these solutions, share information about related efforts that are already underway, or elevate new ideas for advancing the alternative protein industry, we’d love to hear from you!

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Explore key innovation priorities

Review commercial whitespaces, research gaps, technological needs, and investment priorities at each stage of the alternative protein value chain.

How we built this

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Executive summary

Get an overview of GFI’s Solutions initiative and a summary of key resources.

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Full report

Delve into the full report on the motivation, methodology, rationale, and key findings and recommendations of the Solutions initiative.

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Futures wheels analysis

Explore our framework for uncovering second-order or third-order consequences and implications of hypothetical future scenarios to support better decision-making in the present.

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Future-proofing

Discover key findings from GFI’s premortem analysis of potential threats to the widespread adoption of alternative proteins, including strategies to avoid or mitigate the most pressing risks.